Compile Data Set for Download or QSAR
maximum 50k data
Found 52 Enz. Inhib. hit(s) with all data for entry = 50030978
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304675(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304672(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  0.340nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304676(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304667(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304665(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304673(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  0.680nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304670(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304671(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304669(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304680(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  1nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304674(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  1.25nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304678(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304666(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304681(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304667(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304689(5-(4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimid...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304668(CHEMBL605915 | methyl 4-(4-(8-oxa-3-azabicyclo[3.2...)
Affinity DataIC50:  11nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304665(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304679(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  16nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304677(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  20nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304687(3-(2-(1H-indol-5-yl)thieno[3,2-d]pyrimidin-4-yl)-8...)
Affinity DataIC50:  22nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304688(CHEMBL596430 | N-(4-(4-(8-oxa-3-azabicyclo[3.2.1]o...)
Affinity DataIC50:  26.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304684(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3...)
Affinity DataIC50:  32nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304685(5-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3...)
Affinity DataIC50:  35nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  41nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304678(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  46nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  49nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304683(5-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3...)
Affinity DataIC50:  57nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304682(3-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3...)
Affinity DataIC50:  58nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304689(5-(4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimid...)
Affinity DataIC50:  61nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304676(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  80nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304674(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  82nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304666(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  86nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50304686(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3...)
Affinity DataIC50:  100nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304675(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  119nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304681(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  148nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304680(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  179nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304683(5-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3...)
Affinity DataIC50:  246nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304677(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  322nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304672(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  324nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304682(3-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3...)
Affinity DataIC50:  399nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304669(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  423nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304671(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  825nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304679(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-((...)
Affinity DataIC50:  874nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304670(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304673(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thien...)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304685(5-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3...)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304688(CHEMBL596430 | N-(4-(4-(8-oxa-3-azabicyclo[3.2.1]o...)
Affinity DataIC50:  4.37E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304668(CHEMBL605915 | methyl 4-(4-(8-oxa-3-azabicyclo[3.2...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50304684(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3...)
Affinity DataIC50:  6.27E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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