Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50000925
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataKi:  4.5nMAssay Description:Binding affinity of the compound against human thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50011243(2-{4-[(4-Hydroxy-quinazolin-6-ylmethyl)-prop-2-yny...)
Affinity DataKi:  26nMAssay Description:Binding affinity of the compound against thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50011244(6-{[(4-Benzenesulfonyl-phenyl)-prop-2-ynyl-amino]-...)
Affinity DataKi:  27nMAssay Description:Binding affinity of the compound against thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Parke-Davis Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50011243(2-{4-[(4-Hydroxy-quinazolin-6-ylmethyl)-prop-2-yny...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity of the compound against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed