Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50031554
TargetToll-like receptor 8(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315256(CHEMBL1089224 | Methyl{3-[(6-amino-2-butoxy-8-oxo-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at TLR8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315269(CHEMBL1089517 | Methyl{3-[(6-amino-2-methoxyethoxy...)
Affinity DataEC50:  312nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315257(6-Amino-9-benzyl-2-butoxy-9H-purin-8-ol | 6-amino-...)
Affinity DataEC50:  63.7nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315258(CHEMBL1089862 | Methyl 2-[(6-amino-2-butoxy-8-oxo-...)
Affinity DataEC50:  609nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315259(CHEMBL1089863 | Methyl 3-[(6-amino-2-butoxy-8-oxo-...)
Affinity DataEC50:  51.5nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315260(CHEMBL1090529 | Methyl 4-[(6-amino-2-butoxy-8-oxo-...)
Affinity DataEC50:  72.9nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315261(CHEMBL1089220 | Methyl{2-[(6-amino-2-butoxy-8-oxo-...)
Affinity DataEC50:  467nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315256(CHEMBL1089224 | Methyl{3-[(6-amino-2-butoxy-8-oxo-...)
Affinity DataEC50:  50.1nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315262(CHEMBL1089225 | Methyl{4-[(6-amino-2-butoxy-8-oxo-...)
Affinity DataEC50:  10.3nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315263(CHEMBL1089226 | Methyl l 2-{3-[(6-amino-2-butoxy-8...)
Affinity DataEC50:  75nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315264(CHEMBL1089548 | Methyl 3-{3-[(6-amino-2-butoxy-8-o...)
Affinity DataEC50:  87.5nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315265(CHEMBL1092654 | Methyl{5-[(6-amino-2-butoxy-8-oxo-...)
Affinity DataEC50:  8.10nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315266(CHEMBL1092655 | Methyl{3-[(6-amino-2-butoxy-8-oxo-...)
Affinity DataEC50:  108nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315267(CHEMBL1093466 | Methyl{5-[(6-amino-2-butoxy-8-oxo-...)
Affinity DataEC50:  25.7nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315268(CHEMBL1093467 | Ethyl{3-[(6-amino-2-butoxy-8-oxo-7...)
Affinity DataEC50:  188nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50189516(6-amino-9-benzyl-2-(2-methoxyethoxy)-7H-purin-8(9H...)
Affinity DataEC50:  399nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
TargetToll-like receptor 7(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  260nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair