Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 50033957
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354566(CHEMBL1836647)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]N-methylscopolamine from human M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354569(CHEMBL1836646)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]N-methylscopolamine from human M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165008((+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]N-methylscopolamine from human M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354567(CHEMBL1836644)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]nisoxetine from human NET receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354568(CHEMBL1836645)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]N-methylscopolamine from human M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354567(CHEMBL1836644)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]N-methylscopolamine from human M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354569(CHEMBL1836646)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354566(CHEMBL1836647)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354566(CHEMBL1836647)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human beta-2 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed