Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50042943
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50433561(CHEMBL2381408)
Affinity DataKi:  10nMAssay Description:Binding affinity to human MDM2More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50111440(4-(1-carbamoyl-4-methylpentanamide-2-yl-cyclopropy...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human GST-tagged MDM2 assessed as inhibition of binding to full length p53More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50229787((4S,5R)-Nutlin-3 | (rac)-(4,5-bis(4-chlorophenyl)-...)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human GST-tagged MDM2 assessed as inhibition of binding to full length p53More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50392531(CHEMBL407632)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human GST-tagged MDM2 assessed as inhibition of binding to full length p53More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50433562(CHEMBL1818538 | Nutlin-1)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human GST-tagged MDM2 assessed as inhibition of binding to full length p53More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50433564(CHEMBL2381404)
Affinity DataIC50:  313nMAssay Description:Antagonist activity at human MDM2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50433563(CHEMBL2381405)
Affinity DataIC50:  8.90E+3nMAssay Description:Antagonist activity at human MDM2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50433560(CHEMBL2381409)
Affinity DataKd:  55nMAssay Description:Binding affinity to human MDM2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed