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Found 12 Enz. Inhib. hit(s) with all data for entry = 50042931
TargetCytochrome P450 2D6(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433366(CHEMBL2377663)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2D6 assessed as dextromethorphan O-demethylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433367(CHEMBL2377662)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2D6 assessed as dextromethorphan O-demethylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433368(EPEREZOLID | U-100592)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2D6 assessed as dextromethorphan O-demethylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50116067((Linezolid)N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2D6 assessed as dextromethorphan O-demethylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433366(CHEMBL2377663)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2C9 assessed as tolbutamide hydroxylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50116067((Linezolid)N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP1A2 assessed as ethoxyresorufin O-deethylation after 20 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433368(EPEREZOLID | U-100592)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2C9 assessed as tolbutamide hydroxylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50116067((Linezolid)N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2C9 assessed as tolbutamide hydroxylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433366(CHEMBL2377663)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP1A2 assessed as ethoxyresorufin O-deethylation after 20 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433367(CHEMBL2377662)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP1A2 assessed as ethoxyresorufin O-deethylation after 20 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433368(EPEREZOLID | U-100592)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP1A2 assessed as ethoxyresorufin O-deethylation after 20 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433367(CHEMBL2377662)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP2C9 assessed as tolbutamide hydroxylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed