BindingDB PrimarySearch

Found 6 Enz. Inhib. hit(s) with all data for entry = 50005429

Dual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL

BDBM50491985(CHEMBL2391620)

IC50: 1.10E+3nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

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3D Structure (crystal)

Dual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL

BDBM74351(MLS001360529 | SMR001223863 | cid_3694944)

IC50: 1.81E+4nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

Dual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL

BDBM50234316(CHEMBL2391621)

IC50: 3.94E+4nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

Dual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL

BDBM50491987(CHEMBL2391618)

IC50: 1.57E+5nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Dual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL

BDBM50491984(CHEMBL2391619)

IC50: 3.00E+5nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Dual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL

BDBM50491986(CHEMBL2391615)

IC50: 4.91E+5nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed