Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with all data for entry = 50040815
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50257405(Ala-Lys-Lys(epsilon-thioAc)Leu-Met | CHEMBL504711)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of human recombinant SIRT6 assessed as 7-amino-4-methylcoumarin labelled Arg-His-Lys-Lys(epsilon-acetyl) substrate deacetylation after 90 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50257239(CHEMBL447677 | His-Lys-Lys(epsilon-thioAc)-Leu-Met)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of human recombinant SIRT6 assessed as 7-amino-4-methylcoumarin labelled Arg-His-Lys-Lys(epsilon-acetyl) substrate deacetylation after 90 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50326781((S)-Benzyl 6-ethaneselenoamido-1-oxo-1-(phenylamin...)
Affinity DataIC50:  2.85E+5nMAssay Description:Inhibition of human recombinant SIRT6 assessed as 7-amino-4-methylcoumarin labelled Arg-His-Lys-Lys(epsilon-acetyl) substrate deacetylation after 90 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed