BindingDB PrimarySearch

Found 2 Enz. Inhib. hit(s) with all data for entry = 50046649

Prostaglandin G/H synthase 2(Homo sapiens (Human))
Hunan University Of Chinese Medicine

Curated by ChEMBL

BDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)

IC50: 19nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid after 15 mins by fluorescence based assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank
PDB

3D Structure (crystal)

Prostaglandin G/H synthase 1(Ovis aries (Sheep))
Hunan University Of Chinese Medicine

Curated by ChEMBL

BDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)

IC50: 7.84E+4nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid after 15 mins by fluorescence based assayMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase ChEBI
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed