Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 50047371
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50:  120nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 40 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50:  130nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163313(CHEMBL3794179)
Affinity DataIC50:  360nMAssay Description:Inhibition of human gamma-secretase expressed in CHO cells assessed as suppression of amyloid beta 40 production using C100-Flag as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163313(CHEMBL3794179)
Affinity DataIC50:  400nMAssay Description:Inhibition of human gamma-secretase expressed in CHO cells assessed as suppression of amyloid beta 42 production using C100-Flag as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163320(CHEMBL3792858)
Affinity DataIC50:  580nMAssay Description:Inhibition of human gamma-secretase expressed in CHO cells assessed as suppression of amyloid beta 40 production using C100-Flag as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163313(CHEMBL3794179)
Affinity DataIC50:  620nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163311(CHEMBL3793752)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163312(CHEMBL3792849)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50163309(CHEMBL3794005)
Affinity DataIC50:  9.60E+4nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163310(CHEMBL3793199)
Affinity DataIC50:  1.35E+5nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed