Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50047492
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant CYP2D6 using MFC as substrate incubated for 40 mins by fluorimetryMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50117930((4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidine...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as inhibition of tail current after 5 mins by automated whole-cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170903(CHEMBL3805993)
Affinity DataIC50:  85nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170903(CHEMBL3805993)
Affinity DataIC50:  85nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50090677(4-Amino-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfon...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant CYP2C9 using MFC as substrate incubated for 40 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human recombinant CYP3A4 using BFC as substrate incubated for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170912(CHEMBL3805930)
Affinity DataIC50:  480nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170903(CHEMBL3805993)
Affinity DataIC50:  510nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity using 5'-ACTGCTAGAGATTTTCCACACTGACTAAAAGGGTC-[biotin]3' as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170917(CHEMBL3805349)
Affinity DataIC50:  530nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170917(CHEMBL3805349)
Affinity DataIC50:  650nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170912(CHEMBL3805930)
Affinity DataIC50:  660nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170908(CHEMBL3805115)
Affinity DataIC50:  700nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170904(CHEMBL3805505)
Affinity DataIC50:  860nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170904(CHEMBL3805505)
Affinity DataIC50:  860nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170913(CHEMBL3805999)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50236897(3-(furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant CYP1A2 using CEC as substrate incubated for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170914(CHEMBL3805355)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170914(CHEMBL3805355)
Affinity DataIC50:  1.99E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170911(CHEMBL3805358)
Affinity DataIC50:  2.13E+3nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50240772((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human recombinant CYP2C19 using CEC as substrate incubated for 50 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170908(CHEMBL3805115)
Affinity DataIC50:  3.36E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170913(CHEMBL3805999)
Affinity DataIC50:  3.63E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170911(CHEMBL3805358)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170916(CHEMBL3804900)
Affinity DataIC50:  4.43E+3nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170907(CHEMBL3805166)
Affinity DataIC50:  4.45E+3nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170907(CHEMBL3805166)
Affinity DataIC50:  4.46E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170916(CHEMBL3804900)
Affinity DataIC50:  5.05E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170915(CHEMBL3805756)
Affinity DataIC50:  6.65E+3nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170915(CHEMBL3805756)
Affinity DataIC50:  6.67E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170909(CHEMBL3806113)
Affinity DataIC50:  8.12E+3nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170910(CHEMBL3806031)
Affinity DataIC50:  8.66E+3nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170910(CHEMBL3806031)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170905(CHEMBL3805298)
Affinity DataIC50:  9.05E+3nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170909(CHEMBL3806113)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170905(CHEMBL3805298)
Affinity DataIC50:  9.13E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170906(CHEMBL3805797)
Affinity DataIC50:  1.23E+5nMAssay Description:Inhibition of HIV1 integrase using 3'-biotin-labelled and 5'-digoxigenin-labelled oligonucleotide substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50170906(CHEMBL3805797)
Affinity DataIC50:  2.06E+5nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using 5'[digoxigenin]-GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCA-3' as substrate incubated for 1 hr by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed