Compile Data Set for Download or QSAR
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Found 20 Enz. Inhib. hit(s) with all data for entry = 50047433
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50118225(ARL 69931MX | Adenosine triphosphate derivative | ...)
Affinity DataIC50:  0.398nMAssay Description:Antagonist activity at P2Y12 receptor in human platelets assessed as inhibition of ADP-induced platelet aggregation by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50167270(CHEMBL1160364)
Affinity DataIC50:  0.794nMAssay Description:Antagonist activity at P2Y12 receptor in human platelets assessed as inhibition of ADP-induced platelet aggregation by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50167271(CHEMBL3798413)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at P2Y12 receptor in human platelets assessed as inhibition of ADP-induced platelet aggregation by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50167271(CHEMBL3798413)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]-2-Mes-ADP from human P2Y12 receptor by beta-counter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50118223(AR-C67085 | Adenosine triphosphate derivative | CH...)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at P2Y12 receptor in human platelets assessed as inhibition of ADP-induced platelet aggregation by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50397205(AR-C126532XX | AZD-6140 | AZD6140 | BRILINTA | TIC...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50167273(CHEMBL3797316)
Affinity DataIC50:  5.30nMAssay Description:Displacement of [3H]-2-Mes-ADP from human P2Y12 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50167273(CHEMBL3797316)
Affinity DataIC50:  8.30nMAssay Description:Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of ADP-induced platelet aggregation measured for 5 mins by lig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50397204(ELINOGREL)
Affinity DataIC50: <10nMAssay Description:Displacement of [3H]-2-Mes-ADP from human P2Y12 receptor in platelets by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50167272(CHEMBL3798029)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50397203(CHEMBL2172275)
Affinity DataIC50:  29nMAssay Description:Displacement of [3H]-2-Mes-ADP from human P2Y12 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50436962(CHEMBL2402264)
Affinity DataIC50:  40nMAssay Description:Binding affinity to P2Y12 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50439270(CHEMBL2419497)
Affinity DataIC50:  60nMAssay Description:Binding affinity to P2Y12 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50436962(CHEMBL2402264)
Affinity DataIC50:  70nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50439270(CHEMBL2419497)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50397203(CHEMBL2172275)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of ADP-induced platelet aggregation measured for 5 mins by lig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50167272(CHEMBL3798029)
Affinity DataIC50:  440nMAssay Description:Binding affinity to P2Y12 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50397204(ELINOGREL)
Affinity DataIC50: <1.00E+4nMAssay Description:Antagonist activity at P2Y12 receptor in human platelets assessed as inhibition of ADP-induced platelet aggregation by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50366480(ADENOSINE TRIPHOSPHATE | ATP)
Affinity DataIC50:  2.51E+5nMAssay Description:Antagonist activity at P2Y12 receptor in human platelets assessed as inhibition of ADP-induced platelet aggregation by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Galecto Biotech

Curated by ChEMBL
LigandPNGBDBM50167269(CHEMBL1160356)
Affinity DataIC50:  3.16E+5nMAssay Description:Antagonist activity at P2Y12 receptor in human platelets assessed as inhibition of ADP-induced platelet aggregation by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed