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Found 32 Enz. Inhib. hit(s) with all data for entry = 50047690
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183383(CHEMBL3818547)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183406(CHEMBL3818062)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183388(CHEMBL3818015)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183388(CHEMBL3818015)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183391(CHEMBL3818563)
Affinity DataIC50:  0.710nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183395(CHEMBL3818289)
Affinity DataIC50:  0.830nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183383(CHEMBL3818547)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183400(CHEMBL3818364)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183387(CHEMBL3818115)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183406(CHEMBL3818062)
Affinity DataIC50:  2nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183407(CHEMBL3819553)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183395(CHEMBL3818289)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183391(CHEMBL3818563)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183400(CHEMBL3818364)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183387(CHEMBL3818115)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183394(CHEMBL3819120)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183407(CHEMBL3819553)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183383(CHEMBL3818547)
Affinity DataIC50:  26nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183394(CHEMBL3819120)
Affinity DataIC50:  26nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183393(CHEMBL3818970)
Affinity DataIC50:  38nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183406(CHEMBL3818062)
Affinity DataIC50:  40nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183393(CHEMBL3818970)
Affinity DataIC50:  52nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183387(CHEMBL3818115)
Affinity DataIC50:  53nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183395(CHEMBL3818289)
Affinity DataIC50:  59nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  76nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183393(CHEMBL3818970)
Affinity DataIC50:  81nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183400(CHEMBL3818364)
Affinity DataIC50:  111nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183388(CHEMBL3818015)
Affinity DataIC50:  126nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  173nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183407(CHEMBL3819553)
Affinity DataIC50:  295nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183394(CHEMBL3819120)
Affinity DataIC50:  333nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183391(CHEMBL3818563)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed