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Found 20 Enz. Inhib. hit(s) with all data for entry = 50041010
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  0.398nMAssay Description:Compound was tested for inhibiting [3H]pirenzepine Binding to Muscarinic receptor (M1) receptor in Rat Cortex HomogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  0.398nMAssay Description:Compound was tested for inhibiting [3H]pirenzepine Binding to Muscarinic receptor (M1) receptor in Rat Cortex HomogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  0.513nMAssay Description:Evaluation of antagonistic affinity against muscarinic receptor (M2) in guinea pig left atriaMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  0.589nMAssay Description:Compound was tested for inhibiting [3H]pirenzepine Binding to Muscarinic receptor (M1) receptor in Rat Cortex HomogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  1.10nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M3) in Rat Submaxillary GlandMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50403484(CHEMBL306182)
Affinity DataKi:  2.80nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M2) in Rat HeartMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50403484(CHEMBL306182)
Affinity DataKi:  3nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M3) in Rat Submaxillary GlandMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  4nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M2) in Rat HeartMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  4.40nMAssay Description:Compound was tested for binding affinity against Muscarinic acetylcholine receptor M4 in NG 108-15 cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  4.70nMAssay Description:Compound was tested for binding affinity against Muscarinic acetylcholine receptor M4 in NG 108-15 cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50403484(CHEMBL306182)
Affinity DataKi:  5nMAssay Description:Evaluation of antagonistic affinity against muscarinic receptor (M3) in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  6.5nMAssay Description:Compound was tested for inhibiting [3H]pirenzepine Binding to Muscarinic receptor (M1) receptor in Rat Cortex HomogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  10nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M3) in Rat Submaxillary GlandMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  10.5nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M3) in Rat Submaxillary GlandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403484(CHEMBL306182)
Affinity DataKi:  11nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic acetylcholine receptor M4 in NG 108-15 CellMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  12nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M2) in Rat HeartMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  33nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M2) in Rat HeartMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  35nMAssay Description:Evaluation of antagonistic affinity against muscarinic receptor (M3) in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  174nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M3) in Rat Submaxillary GlandMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  794nMAssay Description:Evaluation of antagonistic affinity against muscarinic receptor (M3) in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article