Compile Data Set for Download or QSAR
maximum 50k data
Found 59 Enz. Inhib. hit(s) with all data for entry = 50006033
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010747(CHEMBL543201 | CHEMBL78777 | N,N'-Bis-(3-ethyl-phe...)
Affinity DataIC50:  8nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010758(CHEMBL312600 | N,N'-Bis-(2-iodo-phenyl)-guanidine)
Affinity DataIC50:  13nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010760(CHEMBL310170 | N,N'-Bis-(2-ethyl-phenyl)-guanidine)
Affinity DataIC50:  14nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043978(CHEMBL315051 | N,N'-Di-indan-4-yl-guanidine)
Affinity DataIC50:  29nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...)
Affinity DataIC50:  31nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010784(CHEMBL81070 | N,N'-Bis-(4-bromo-phenyl)-guanidine)
Affinity DataIC50:  33nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043950(CHEMBL90508 | N-(2-Iodo-phenyl)-N'-naphthalen-1-yl...)
Affinity DataIC50:  40nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010739(CHEMBL79437 | N,N'-Bis-(3-propyl-phenyl)-guanidine)
Affinity DataIC50:  42nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010791(CHEMBL309603 | N,N'-Di-m-tolyl-guanidine)
Affinity DataIC50:  43nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043968(CHEMBL91713 | N-(3-Ethyl-phenyl)-N'-naphthalen-1-y...)
Affinity DataIC50:  54nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010806(CHEMBL78306 | N,N'-Bis-(5,6,7,8-tetrahydro-naphtha...)
Affinity DataIC50:  59nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043963(CHEMBL88660 | N-(3-Ethyl-phenyl)-4-phenyl-piperidi...)
Affinity DataIC50:  60nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043955(CHEMBL88932 | N-Naphthalen-1-yl-N'-m-tolyl-guanidi...)
Affinity DataIC50:  75nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043977(CHEMBL543434 | CHEMBL91628 | N,N'-Bis-(3-ethyl-phe...)
Affinity DataIC50:  82nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010755(CHEMBL280243 | N,N'-Bis-(2-isopropyl-phenyl)-guani...)
Affinity DataIC50:  88nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043947(CHEMBL89344 | N-(2-Isopropyl-phenyl)-N'-naphthalen...)
Affinity DataIC50:  91nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043970(CHEMBL91791 | N,N'-Di-naphthalen-2-yl-guanidine)
Affinity DataIC50:  92nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010789(CHEMBL82078 | N,N'-Bis-(3-isopropyl-phenyl)-guanid...)
Affinity DataIC50:  96nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010797(CHEMBL81678 | N,N'-Bis-(3-iodo-phenyl)-guanidine)
Affinity DataIC50:  125nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043951(CHEMBL90975 | N-Benzyl-N'-naphthalen-1-yl-guanidin...)
Affinity DataIC50:  140nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010810(CHEMBL79509 | N,N'-Di-naphthalen-1-yl-guanidine)
Affinity DataIC50:  165nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043953(CHEMBL430455 | N-Indan-2-yl-N'-naphthalen-1-yl-gua...)
Affinity DataIC50:  240nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010754(CHEMBL81626 | N,N'-Bis-(4-isopropyl-phenyl)-guanid...)
Affinity DataIC50:  242nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010736(CHEMBL78083 | N,N'-Bis-(4-ethyl-phenyl)-guanidine)
Affinity DataIC50:  245nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043964(CHEMBL330551 | N-Methyl-N,N'-di-m-tolyl-guanidine)
Affinity DataIC50:  247nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043946(CHEMBL314423 | N-(3-Ethyl-phenyl)-2,3-dihydro-indo...)
Affinity DataIC50:  341nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043980(CHEMBL431214 | N-Naphthalen-1-yl-4-phenyl-piperidi...)
Affinity DataIC50:  343nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043945(CHEMBL91222 | N,N'-Bis-(3-methoxy-phenyl)-guanidin...)
Affinity DataIC50:  351nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010786(CHEMBL78411 | N,N'-Bis-(2-tert-butyl-phenyl)-guani...)
Affinity DataIC50:  356nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010769(CHEMBL556117 | CHEMBL77675 | N,N'-Diphenyl-guanidi...)
Affinity DataIC50:  397nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010743(N,N'-Di-p-tolyl-guanidine)
Affinity DataIC50:  535nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043960(CHEMBL328986 | N'-(3-Ethyl-phenyl)-N-methyl-N-naph...)
Affinity DataIC50:  1.00E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043954(CHEMBL91145 | N-Naphthalen-1-yl-piperidine-1-carbo...)
Affinity DataIC50:  1.07E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043976(CHEMBL89811 | N-(3-Ethyl-phenyl)-N,N'-dimethyl-N'-...)
Affinity DataIC50:  1.21E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043949(C-[Bis-(3,4-dihydro-2H-quinolin-1-yl)]-methyleneam...)
Affinity DataIC50:  1.37E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043965(CHEMBL314710 | N-Naphthalen-1-yl-azepane-1-carboxa...)
Affinity DataIC50:  1.41E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043956(CHEMBL420979 | N-Methyl-N'-naphthalen-1-yl-N-m-tol...)
Affinity DataIC50:  1.86E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010745(CHEMBL310729 | N,N'-Bis-(2-methoxy-phenyl)-guanidi...)
Affinity DataIC50:  1.99E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043961(CHEMBL92095 | N'-Anthracen-1-yl-N-methyl-N-naphtha...)
Affinity DataIC50:  2.10E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043974(CHEMBL420245 | N-Ethyl-N-(3-ethyl-phenyl)-N'-napht...)
Affinity DataIC50:  2.19E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043971(CHEMBL88146 | N-Ethyl-N'-(3-ethyl-phenyl)-N'-methy...)
Affinity DataIC50:  2.29E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043958(CHEMBL554054 | CHEMBL92484 | N-(3-Ethyl-phenyl)-N-...)
Affinity DataIC50:  2.54E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043944(CHEMBL265549 | N-Methyl-N-naphthalen-1-yl-N'-(3-ni...)
Affinity DataIC50:  2.64E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043972(CHEMBL91946 | N-(3-Amino-phenyl)-N-methyl-N'-napht...)
Affinity DataIC50:  2.70E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043969(CHEMBL431462 | N'-(3-Azido-phenyl)-N-methyl-N-naph...)
Affinity DataIC50:  2.74E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043983(CHEMBL90643 | N-Methyl-N'-naphthalen-1-yl-N-phenyl...)
Affinity DataIC50:  2.90E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043948(CHEMBL90326 | N-(3-Azido-phenyl)-N-methyl-N'-napht...)
Affinity DataIC50:  3.02E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043959(CHEMBL88465 | N-Methyl-N,N'-di-naphthalen-1-yl-gua...)
Affinity DataIC50:  4.80E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043952(CHEMBL90809 | N-Ethyl-N,N'-di-naphthalen-1-yl-guan...)
Affinity DataIC50:  6.13E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043957(CHEMBL421364 | N-Methyl-N'-naphthalen-1-yl-N-(3-ni...)
Affinity DataIC50:  6.26E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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