Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 50006312
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047468(CHEMBL290534 | Pyridin-3-ylmethyl-(3,7,11-trimethy...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047461(Benzyl-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-tri...)
Affinity DataIC50:  10nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047468(CHEMBL290534 | Pyridin-3-ylmethyl-(3,7,11-trimethy...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047461(Benzyl-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-tri...)
Affinity DataIC50:  100nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047470(CHEMBL37555 | Pyridin-4-ylmethyl-(3,7,11-trimethyl...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047464(CHEMBL37925 | Ethyl-(3,7,11-trimethyl-dodeca-2,6,1...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047459((3,7,11-Trimethyl-dodeca-2,6,10-trienyl)-(2,6,10-t...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047458(CHEMBL37609 | Ethyl-pyridin-3-ylmethyl-(3,7,11-tri...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047460(CHEMBL284514 | Pyridin-3-ylmethyl-(3,7,11-trimethy...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047463((3,7-Dimethyl-octa-2,6-dienyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047462(CHEMBL38101 | Pyridin-3-ylmethyl-(2,6,10-trimethyl...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047469(3-(3,7,11-Trimethyl-dodeca-2,6,10-trienyloxymethyl...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047467(Bis-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-amine...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047465(CHEMBL37832 | Ethyl-bis-(3,7,11-trimethyl-dodeca-2...)
Affinity DataIC50:  1.82E+5nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047466(3,7,11-Trimethyl-1-(3,7,11-trimethyl-dodeca-2,6,10...)
Affinity DataIC50:  8.28E+5nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed