Compile Data Set for Download or QSAR
maximum 50k data
Found 60 Enz. Inhib. hit(s) with all data for entry = 50007346
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataIC50:  500nMAssay Description:The quantity of compound required to reduce WT Reverse transcriptase activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50061574(1-Benzyl-2-(2,6-difluoro-phenyl)-4-methyl-1H-benzo...)
Affinity DataIC50:  1.60E+3nMAssay Description:The quantity of compound required to reduce WT Reverse transcriptase activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50061572(1-(2,6-Difluoro-benzyl)-2-phenyl-1H-benzoimidazole...)
Affinity DataIC50:  1.60E+4nMAssay Description:The quantity of compound required to reduce WT Reverse transcriptase activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50061575(1-Benzyl-2-(2,6-difluoro-phenyl)-1H-benzoimidazole...)
Affinity DataIC50:  1.86E+4nMAssay Description:The quantity of compound required to reduce WT Reverse transcriptase activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17666(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataIC50:  1.10E+5nMAssay Description:The quantity of compound required to reduce WT Reverse transcriptase activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataIC50:  2.00E+5nMAssay Description:The quantity of compound required to reduce WT Reverse transcriptase activity by 50%More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  2.30E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with Y188C (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17666(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50: >2.00E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with V106A (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50036504((R-(-))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  1.25E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with V106A (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17666(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  1.85E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with NL4-3(WT) NNRTI (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  300nMAssay Description:Cross Resistance (antiviral activity) of the compound with L100I (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  9.70E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with V108I (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  1.22E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with L100I (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50036504((R-(-))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50: >1.74E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with 4xAZT/L100I (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cyt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  100nMAssay Description:Cross Resistance (antiviral activity) of the compound with L74V (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  700nMAssay Description:Cross Resistance (antiviral activity) of the compound with L74V (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17666(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  1.04E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with V108I (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  2.00E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with V106A (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  2.80E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with V108I (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate vMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17666(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  1.52E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with Y181C (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  1.67E+4nMAssay Description:Cross Resistance(antiviral activity) of the compound with K101E (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  8.10E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with K103N (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50036504((R-(-))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  300nMAssay Description:Cross Resistance (antiviral activity) of the compound with NL4-3(WT) NNRTI (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50036504((R-(-))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  1.74E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with L100I (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  1.70E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with NL4-3(WT) NNRTI (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17666(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  2.30E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with V179D (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17666(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  1.17E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with Y188C (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  3.50E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with 4xAZT/Y181C (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cyt...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17666(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  840nMAssay Description:Cross Resistance (antiviral activity) of the compound with 4xAZT/L100I (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cyt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  500nMAssay Description:Cross Resistance (antiviral activity) of the compound with V179D (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50036504((R-(-))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  300nMAssay Description:Cross Resistance (antiviral activity) of the compound with 4xAZT (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17666(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  270nMAssay Description:Cross Resistance (antiviral activity) of the compound with 4xAZT (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50036504((R-(-))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  1.74E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with K103N (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50036504((R-(-))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  1.10E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with A98G (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  100nMAssay Description:Cross Resistance (antiviral activity) of the compound with 4xAZT (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  1.50E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with 4xAZT (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  3.10E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with V179D (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50: >2.00E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with K103N (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  1.45E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with 4xAZT/Y181C (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cyt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50036504((R-(-))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  1.74E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with K101E (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  6.00E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with Y181C (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17666(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  4.75E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with A98G (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  500nMAssay Description:Cross Resistance (antiviral activity) of the compound with NL4-3(WT) NNRTI (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17666(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50: >2.00E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with K101E (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50036504((R-(-))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  2.40E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with V108I (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50036504((R-(-))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50:  6.20E+3nMAssay Description:Cross Resistance (antiviral activity) of the compound with V179D (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50:  1.77E+4nMAssay Description:Cross Resistance(antiviral activity) of the compound with A98G (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM10245(3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....)
Affinity DataEC50: >2.00E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with V106A (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50036504((R-(-))-8-Methyl-6,7,8,9-tetrahydro-2H-2,7,9a-tria...)
Affinity DataEC50: >1.74E+4nMAssay Description:Cross Resistance (antiviral activity) of the compound with Y188C (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cytopathi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  200nMAssay Description:Cross Resistance (antiviral activity) of the compound with 4xAZT/L100I (Nonnucleoside reverse transcriptase inhibitor) resistant HIV isolate from cyt...More data for this Ligand-Target Pair
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