Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50008053
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(CHEMBL281025 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  50nMAssay Description:Compound was evaluated in vitro for the inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(CHEMBL281025 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  60nMAssay Description:Compound was evaluated for inhibitory activity against cholesteryl ester transfer proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(CHEMBL281025 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  80nMAssay Description:Compound was evaluated for inhibitory activity against cholesteryl ester transfer protein, reported from fungusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070344(CHEMBL26950 | Thiophene-2-sulfonic acid [2-(3-{[((...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070337(CHEMBL27154 | [3,3']Bithiophenyl-5-sulfonic acid [...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070341(CHEMBL26151 | Pyridine-3-sulfonic acid [2-(3-{[((E...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070345(CHEMBL26964 | Thiophene-2-sulfonic acid [2-(3-{[((...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070343(CHEMBL26596 | Thiazole-2-sulfonic acid [2-(3-{[((E...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070350(CHEMBL284197 | N-[2-(3-{[((E)-6,6-Dimethyl-hept-2-...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070331(4-Cyano-N-[2-(3-{[((E)-6,6-dimethyl-hept-2-en-4-yn...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070346(CHEMBL27941 | [2,3']Bithiophenyl-5-sulfonic acid [...)
Affinity DataIC50:  210nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070342(CHEMBL26077 | Thiophene-2-sulfonic acid cyclopropy...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070349(CHEMBL26597 | Thiophene-3-sulfonic acid [2-(3-{[((...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070333(CHEMBL281666 | N-[2-(3-{[((E)-6,6-Dimethyl-hept-2-...)
Affinity DataIC50:  255nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070348(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-{3-[3-(t...)
Affinity DataIC50:  290nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070339(4-Bromo-thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070347(4-Bromo-N-[2-(3-{[((E)-6,6-dimethyl-hept-2-en-4-yn...)
Affinity DataIC50:  330nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070338(5-Bromo-thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50:  390nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070335(CHEMBL280972 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  450nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070334(Benzo[b]thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Rattus norvegicus)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(CHEMBL281025 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  6.00E+3nMAssay Description:Compound was evaluated in vitro for the inhibition of rat liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070336(CHEMBL26082 | Thiophene-2-sulfonic acid [3-(3-{[((...)
Affinity DataIC50:  6.40E+3nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070332(CHEMBL27195 | [2,2']Bithiophenyl-5-sulfonic acid [...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed