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Found 21 Enz. Inhib. hit(s) with all data for entry = 50008261
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071948(CHEMBL314535 | Urea analogue)
Affinity DataKi:  30nMAssay Description:Compound was tested for inhibition of blood coagulation protein factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071942(3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...)
Affinity DataKi:  102nMAssay Description:Compound was tested for inhibition of blood coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071946(3-(3-{4-[(Z)-amino(imino)methyl]phenyl}-2-oxo-1,3-...)
Affinity DataKi:  120nMAssay Description:Compound was tested for inhibition of trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071942(3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...)
Affinity DataKi:  282nMAssay Description:Compound was tested for inhibition of trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071941(3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-tetrahydro-py...)
Affinity DataKi:  400nMAssay Description:Compound was tested for inhibition of blood coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071946(3-(3-{4-[(Z)-amino(imino)methyl]phenyl}-2-oxo-1,3-...)
Affinity DataKi:  800nMAssay Description:Compound was tested for inhibition of blood coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071948(CHEMBL314535 | Urea analogue)
Affinity DataKi:  1.10E+3nMAssay Description:Compound was tested for inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071945(3-[3-(1-Benzyl-piperidin-4-yl)-ureido]-benzamidine...)
Affinity DataKi: >1.20E+3nMAssay Description:Compound was tested for inhibition of trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071947(4-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...)
Affinity DataKi: >1.60E+3nMAssay Description:Compound was tested for inhibition of trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071942(3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...)
Affinity DataKi:  2.00E+3nMAssay Description:Compound was tested for inhibition of thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071943(3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-imidazolidin-...)
Affinity DataKi:  2.10E+3nMAssay Description:Compound was tested for inhibition of blood coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071944(4-[3-(3-Carbamimidoyl-phenyl)-2-oxo-[1,3]diazepan-...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was tested for inhibition of blood coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071948(CHEMBL314535 | Urea analogue)
Affinity DataKi:  4.20E+3nMAssay Description:Compound was tested for inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071945(3-[3-(1-Benzyl-piperidin-4-yl)-ureido]-benzamidine...)
Affinity DataKi:  4.90E+3nMAssay Description:Compound was tested for inhibition of blood coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071941(3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-tetrahydro-py...)
Affinity DataKi:  7.30E+3nMAssay Description:Compound was tested for inhibition of thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071947(4-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...)
Affinity DataKi:  7.50E+3nMAssay Description:Compound was tested for inhibition of blood coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071946(3-(3-{4-[(Z)-amino(imino)methyl]phenyl}-2-oxo-1,3-...)
Affinity DataKi:  9.30E+3nMAssay Description:Compound was tested for inhibition of thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071943(3-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-imidazolidin-...)
Affinity DataKi:  1.10E+4nMAssay Description:Compound was tested for inhibition of thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071945(3-[3-(1-Benzyl-piperidin-4-yl)-ureido]-benzamidine...)
Affinity DataKi: >2.10E+4nMAssay Description:Compound was tested for inhibition of thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071947(4-[3-(1-Benzyl-piperidin-4-yl)-2-oxo-[1,3]diazepan...)
Affinity DataKi: >2.10E+4nMAssay Description:Compound was tested for inhibition of thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071944(4-[3-(3-Carbamimidoyl-phenyl)-2-oxo-[1,3]diazepan-...)
Affinity DataKi: >2.10E+4nMAssay Description:Compound was tested for inhibition of thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed