Compile Data Set for Download or QSAR
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Found 32 Enz. Inhib. hit(s) with all data for entry = 50008441
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM577((3S)-oxolan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-...)
Affinity DataKi: <0.100nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073365((S)-2-(3-{(R)-3-[Cyclopentylmethyl-(4-methoxy-phen...)
Affinity DataKi:  7nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073364(CHEMBL122542 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  15nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073353(CHEMBL332611 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  17nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073350(CHEMBL121146 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  20nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073346(CHEMBL119998 | N-{(S)-3-[Cyclopentylmethyl-(4-meth...)
Affinity DataKi:  20nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073360(CHEMBL333312 | N-[(S)-3-(3-Benzyl-1-phenethyl-urei...)
Affinity DataKi:  22nMAssay Description:Binding affinity of the compound against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073356(1N-[3-cyclopentylmethyl(4-methoxyphenyl)sulfonamid...)
Affinity DataKi:  27nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073359(1N-[3-cyclopentylmethyl(4-methoxyphenyl)sulfonamid...)
Affinity DataKi:  29nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073340(CHEMBL120843 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  38nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073347(CHEMBL331105 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  38nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073366(CHEMBL122936 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  40nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073362(CHEMBL264550 | N-Cyclopentylmethyl-N-{(S)-2-hydrox...)
Affinity DataKi:  43nMAssay Description:Binding affinity of the compound against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073354(CHEMBL331879 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  50nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073357(CHEMBL332564 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  65nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073363(CHEMBL121254 | N-{(S)-3-[Cyclopentylmethyl-(4-meth...)
Affinity DataKi:  66nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073341(1N-[3-cyclopentylmethyl(4-methoxyphenyl)sulfonamid...)
Affinity DataKi:  76nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073348(CHEMBL124161 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  104nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073339(CHEMBL331429 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  125nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073355(CHEMBL123186 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  173nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073351(CHEMBL333037 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  200nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073352(1N-[3-cyclopentylmethyl(4-methoxyphenyl)sulfonamid...)
Affinity DataKi:  220nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073338(CHEMBL121023 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  300nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073358(Benzyl-{(S)-3-[cyclopentylmethyl-(4-methoxy-benzen...)
Affinity DataKi:  600nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073361(1N-[3-cyclopentylmethyl(4-methoxyphenyl)sulfonamid...)
Affinity DataKi:  680nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073349(CHEMBL121036 | {(S)-3-[Cyclopentylmethyl-(4-methox...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073337(CHEMBL122564 | N-[(S)-3-(3-tert-Butyl-1-phenethyl-...)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity of the compound against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073342(CHEMBL121375 | N-Cyclopentylmethyl-N-[(S)-2-hydrox...)
Affinity DataKi:  3.40E+3nMAssay Description:Binding affinity of the compound against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073344(CHEMBL331655 | N-Cyclopentylmethyl-N-{(S)-2-hydrox...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of the compound against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073336(CHEMBL121376 | N-Cyclopentylmethyl-N-[(S)-2-hydrox...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of the compound against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073345(CHEMBL332806 | N-Cyclopentylmethyl-N-[(S)-2-hydrox...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of the compound against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073343(CHEMBL120052 | N-Cyclopentylmethyl-N-[(S)-2-hydrox...)
Affinity DataKi: >2.00E+4nMAssay Description:Binding affinity of the compound against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed