Reaction Details  Report a problem with these data
Cell Reactant:
Cyclin-dependent kinase 2
Syringe Reactant:
BDBM225314
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
05/10/17
ΔG°:
-30.4±0 (kJ/mole)
Temperature:
298±0 (K)
ΔH° :
-9.8±0.54 (kJ/mole)
ΔS° :
0.0691±0.0004 (kJ/mole-K)
Citation
 D3R, DD CSAR CDK2-CyclinA D3R 219:0 (2015) [PubMed] 
Cell React
Name:
Cyclin-dependent kinase 2
Synonyms:
CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
33938.17
Organism:
Homo sapiens (Human)
Description:
P24941
Residue:
298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
  
Syringe React
Name:
BDBM225314
Synonyms:
CS9
Type:
Small Organic Molecule
Emp. Form.:
C15H14F3N3O2
Mol. Mass.:
325.2858
SMILES:
FC(F)(F)Oc1ccc(CC(=O)Nc2cc([nH]n2)C2CC2)cc1
Structure:
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