Reaction Details Report a problem with these data
Target
Galectin-3
Ligand
BDBM508748
Substrate
n/a
Meas. Tech.
fluorescence anisotropy assay
Kd
6600±n/a nM
Citation
 Zetterberg, F Galactoside inhibitor of galectins US Patent  US11046725 Publication Date 6/29/2021 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Homo sapiens (Human)
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM508748
Synonyms:
3-Chloro-4-methylphenyl 3-deoxy-3-[4-(2-hydroxythiazol-4-yl)-1H-1,2,3-triazol-1-yl]-1-thio-α-D-galactopyranoside | US11046725, Example 26
Type:
Small organic molecule
Emp. Form.:
C18H19ClN4O5S2
Mol. Mass.:
470.95
SMILES:
Cc1ccc(S[C@H]2OC(CO)[C@H](O)[C@@H](C2O)n2cc(nn2)-c2csc(O)n2)cc1Cl |r|
Structure:
Search PDB for entries with ligand similarity: