Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM530480
Substrate
n/a
EC50
460±n/a nM
Citation
 L., PH; A., JJ; V., DS AMINOIMIDAZOLE FPR2 AGONISTS WIPO 0:0 (2022) [PubMed] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM530480
Synonyms:
WO2022076764, Example 9
Type:
Small organic molecule
Emp. Form.:
C28H19F4N3O3
Mol. Mass.:
521.4624
SMILES:
COc1cc(F)c(c(F)c1)-n1cc(nc1NC(=O)c1ccc(OC(F)F)cc1)-c1ccc2ccccc2c1 |(1.24,-8.54,;2.27,-7.4,;1.79,-5.93,;.28,-5.61,;-.19,-4.15,;-1.7,-3.83,;.84,-3,;2.34,-3.32,;3.38,-2.18,;2.82,-4.79,;.36,-1.54,;-1.1,-1.06,;-1.1,.48,;.36,.95,;1.27,-.29,;2.81,-.29,;3.58,1.04,;2.81,2.38,;5.12,1.04,;5.89,-.29,;7.43,-.29,;8.2,1.04,;9.74,1.04,;10.51,2.38,;9.74,3.71,;12.05,2.38,;7.43,2.38,;5.89,2.38,;-2.35,1.38,;-3.75,.76,;-5,1.66,;-4.84,3.19,;-6.09,4.1,;-5.92,5.63,;-4.52,6.26,;-3.27,5.35,;-3.43,3.82,;-2.19,2.92,)|
Structure:
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