Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM38445
Substrate
n/a
Meas. Tech.
Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism
IC50
11810±n/a nM
Citation
 PubChem, PC Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM38445
Synonyms:
MLS000066749 | N-allyl-2-(1-pyrrolidinyl)-4-quinazolinamine | N-prop-2-enyl-2-(1-pyrrolidinyl)-4-quinazolinamine | N-prop-2-enyl-2-pyrrolidin-1-yl-quinazolin-4-amine | N-prop-2-enyl-2-pyrrolidin-1-ylquinazolin-4-amine | SMR000082774 | allyl-(2-pyrrolidinoquinazolin-4-yl)amine | cid_2243399
Type:
Small organic molecule
Emp. Form.:
C15H18N4
Mol. Mass.:
254.3302
SMILES:
C=CCNc1nc(nc2ccccc12)N1CCCC1
Structure:
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