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Target
Streptokinase A
Ligand
BDBM57665
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
22027±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM57665
Synonyms:
(2,3-dimethylphenyl)-[(E)-(5-imino-3-methyl-1-phenyl-2-pyrazolin-4-ylidene)amino]amine | MLS000374985 | N-[(E)-(5-azanylidene-3-methyl-1-phenyl-pyrazol-4-ylidene)amino]-2,3-dimethyl-aniline | N-[(E)-(5-imino-3-methyl-1-phenyl-4-pyrazolylidene)amino]-2,3-dimethylaniline | N-[(E)-(5-imino-3-methyl-1-phenylpyrazol-4-ylidene)amino]-2,3-dimethylaniline | SMR000254339 | cid_6414251
Type:
Small organic molecule
Emp. Form.:
C18H19N5
Mol. Mass.:
305.377
SMILES:
Cc1nn(c(N)c1N=Nc1cccc(C)c1C)-c1ccccc1 |w:8.9|
Structure:
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