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Target
Bcl-2-like protein 11
Ligand
BDBM67044
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM67044
Synonyms:
MLS002472295 | N-(2-bromobenzyl)-9,10,10-triketo-6-[4-(trifluoromethoxy)phenyl]thioxanthene-1-carboxamide | N-[(2-bromophenyl)methyl]-9,10,10-trioxo-6-[4-(trifluoromethoxy)phenyl]-1-thioxanthenecarboxamide | N-[(2-bromophenyl)methyl]-9,10,10-trioxo-6-[4-(trifluoromethoxy)phenyl]thioxanthene-1-carboxamide | N-[(2-bromophenyl)methyl]-9,10,10-tris(oxidanylidene)-6-[4-(trifluoromethyloxy)phenyl]thioxanthene-1-carboxamide | SMR001395446 | cid_44144212
Type:
Small organic molecule
Emp. Form.:
C28H17BrF3NO5S
Mol. Mass.:
616.402
SMILES:
FC(F)(F)Oc1ccc(cc1)-c1ccc2C(=O)c3c(cccc3S(=O)(=O)c2c1)C(=O)NCc1ccccc1Br
Structure:
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