Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM67074
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM67074
Synonyms:
(2S)-2-[(2-fluorophenyl)sulfonylamino]-3-methyl-butyric acid [2-keto-2-(3-sulfamoylanilino)ethyl] ester | (2S)-2-[(2-fluorophenyl)sulfonylamino]-3-methylbutanoic acid [2-oxo-2-(3-sulfamoylanilino)ethyl] ester | MLS002252730 | SMR001315066 | [2-oxidanylidene-2-[(3-sulfamoylphenyl)amino]ethyl] (2S)-2-[(2-fluorophenyl)sulfonylamino]-3-methyl-butanoate | [2-oxo-2-(3-sulfamoylanilino)ethyl] (2S)-2-[(2-fluorophenyl)sulfonylamino]-3-methylbutanoate | cid_16245201
Type:
Small organic molecule
Emp. Form.:
C19H22FN3O7S2
Mol. Mass.:
487.522
SMILES:
CC(C)[C@H](NS(=O)(=O)c1ccccc1F)C(=O)OCC(=O)Nc1cccc(c1)S(N)(=O)=O
Structure:
Search PDB for entries with ligand similarity: