Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM68329
Substrate
n/a
Meas. Tech.
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 4
IC50
12300±n/a nM
Citation
 PubChem, PC SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 4 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM68329
Synonyms:
4-chloranyl-N-(2-methoxy-5-morpholin-4-ylsulfonyl-phenyl)benzamide | 4-chloro-N-(2-methoxy-5-morpholin-4-ylsulfonylphenyl)benzamide | 4-chloro-N-(2-methoxy-5-morpholinosulfonyl-phenyl)benzamide | 4-chloro-N-[2-methoxy-5-(4-morpholinylsulfonyl)phenyl]benzamide | MLS-0397235.0001 | cid_6484583
Type:
Small organic molecule
Emp. Form.:
C18H19ClN2O5S
Mol. Mass.:
410.872
SMILES:
COc1ccc(cc1NC(=O)c1ccc(Cl)cc1)S(=O)(=O)N1CCOCC1
Structure:
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