Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM68312
Substrate
n/a
Meas. Tech.
SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 3
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM68312
Synonyms:
4-fluoranyl-N-(2-methoxy-5-morpholin-4-ylsulfonyl-phenyl)-3-methyl-1-benzothiophene-2-carboxamide | 4-fluoro-N-(2-methoxy-5-morpholin-4-ylsulfonylphenyl)-3-methyl-1-benzothiophene-2-carboxamide | 4-fluoro-N-(2-methoxy-5-morpholinosulfonyl-phenyl)-3-methyl-benzothiophene-2-carboxamide | 4-fluoro-N-[2-methoxy-5-(4-morpholinylsulfonyl)phenyl]-3-methyl-1-benzothiophene-2-carboxamide | MLS-0435538.0001 | cid_16303023
Type:
Small organic molecule
Emp. Form.:
C21H21FN2O5S2
Mol. Mass.:
464.53
SMILES:
COc1ccc(cc1NC(=O)c1sc2cccc(F)c2c1C)S(=O)(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: