Reaction Details Report a problem with these data
Target
Caspase-7
Ligand
BDBM53108
Substrate
n/a
Meas. Tech.
Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7
EC50
>85247±n/a nM
Citation
 PubChem, PC Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 PubChem Bioassay (2010)[AID] 
Target
Name:
Caspase-7
Synonyms:
Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase
Type:
Enzyme
Mol. Mass.:
34273.91
Organism:
Homo sapiens (Human)
Description:
P55210
Residue:
303
Sequence:
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
  
Inhibitor
Name:
BDBM53108
Synonyms:
2-[(6,7-dihydroxy-2-keto-chromen-4-yl)methylamino]benzoic acid methyl ester | 2-[(6,7-dihydroxy-2-oxo-1-benzopyran-4-yl)methylamino]benzoic acid methyl ester | MLS001214762 | SMR000543544 | cid_5574594 | methyl 2-[(6,7-dihydroxy-2-oxochromen-4-yl)methylamino]benzoate | methyl 2-[[6,7-bis(oxidanyl)-2-oxidanylidene-chromen-4-yl]methylamino]benzoate
Type:
Small organic molecule
Emp. Form.:
C18H15NO6
Mol. Mass.:
341.3148
SMILES:
COC(=O)c1ccccc1NCc1cc(=O)oc2cc(O)c(O)cc12
Structure:
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