Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM32308
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay
IC50
5470±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM32308
Synonyms:
(Z)-1-phenyl-3-(5-phenyl-2-furanyl)-2-propen-1-one | (Z)-1-phenyl-3-(5-phenyl-2-furyl)prop-2-en-1-one | (Z)-1-phenyl-3-(5-phenylfuran-2-yl)prop-2-en-1-one | MLS000722313 | SMR000236018 | cid_5708162
Type:
Small organic molecule
Emp. Form.:
C19H14O2
Mol. Mass.:
274.3133
SMILES:
O=C(\C=C/c1ccc(o1)-c1ccccc1)c1ccccc1
Structure:
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