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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78619
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
965±73 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78619
Synonyms:
2-amino-N'-(2,3-dimethoxybenzylidene)-4-methyl-1,3-thiazole-5-carbohydrazide | 2-amino-N-[(2,3-dimethoxybenzylidene)amino]-4-methyl-thiazole-5-carboxamide | 2-amino-N-[(2,3-dimethoxyphenyl)methylideneamino]-4-methyl-1,3-thiazole-5-carboxamide | 2-amino-N-[(2,3-dimethoxyphenyl)methylideneamino]-4-methyl-5-thiazolecarboxamide | 2-azanyl-N-[(2,3-dimethoxyphenyl)methylideneamino]-4-methyl-1,3-thiazole-5-carboxamide | MLS000545717 | SMR000162968 | cid_729197
Type:
Small organic molecule
Emp. Form.:
C14H16N4O3S
Mol. Mass.:
320.367
SMILES:
COc1cccc(C=NNC(=O)c2sc(N)nc2C)c1OC
Structure:
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