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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM79216
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM79216
Synonyms:
5'-Guanidinonaltrindole di(trifluoroacetate) salt hydrate, hydrochloride | MLS002153484 | SMR001230831 | cid_25102761
Type:
Small organic molecule
Emp. Form.:
C29H30F3N5O5
Mol. Mass.:
585.5742
SMILES:
OC(=O)C(F)(F)F.[H][C@@]12Oc3c4c(C[C@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2ccc(cc12)N=C(N)N)ccc3O |wU:24.27,23.22,14.13,8.6,TLB:17:16:24:11.13.12,(9.51,1.33,;8.18,2.1,;8.18,3.64,;6.85,1.33,;5.51,.56,;6.07,2.67,;7.62,,;5.31,11.99,;5.7,13.24,;4.17,13.21,;3.55,14.61,;4.93,15.43,;4.93,16.97,;6.27,17.74,;7.6,16.97,;8.25,18.11,;6.95,16.96,;7.27,18.47,;6.13,19.5,;5.65,20.96,;4.62,19.82,;5.82,16.46,;5.95,15.23,;6.27,14.66,;7.6,15.43,;9.12,15.7,;8.66,14.36,;8.34,12.88,;6.92,12.34,;7,10.84,;8.45,10.44,;9.13,9.03,;10.69,8.92,;11.56,10.23,;10.84,11.63,;9.28,11.7,;13.1,10.15,;13.79,8.77,;15.33,8.69,;12.95,7.48,;3.55,17.8,;2.16,17.01,;2.16,15.4,;.83,14.63,)|
Structure:
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