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Targetputative hexokinase HKDC1
LigandBDBM80801
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of activators of hexokinase domain containing I (HKDC1)
EC50>80000±n/a nM
Citation PubChem, PC Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
putative hexokinase HKDC1
Name:putative hexokinase HKDC1
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:102520.24
Organism:Homo sapiens (Human)
Description:gi_156151420
Residue:917
Sequence:
MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR
GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV
QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL
YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG
LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH
PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT
REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT
FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT
MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI
RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI
VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA
ALITAVAKRLQQAQKEN
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  Blast E-value cutoff:
BDBM80801
NameBDBM80801
Synonyms:8-[2-[(Z)-(1-cyclohexyl-4,6-dioxo-2-sulfanylidene-1,3-diazinan-5-ylidene)methyl]hydrazinyl]-1,3,7-trimethylpurine-2,6-dione | 8-[2-[(Z)-[1-cyclohexyl-4,6-bis(oxidanylidene)-2-sulfanylidene-1,3-diazinan-5-ylidene]methyl]hydrazinyl]-1,3,7-trimethyl-purine-2,6-dione | 8-[N'-[(Z)-(1-cyclohexyl-4,6-diketo-2-thioxo-hexahydropyrimidin-5-ylidene)methyl]hydrazino]-1,3,7-trimethyl-xanthine | 8-[[(Z)-(1-cyclohexyl-4,6-dioxo-2-sulfanylidene-1,3-diazinan-5-ylidene)methyl]hydrazo]-1,3,7-trimethylpurine-2,6-dione | 8-{N'-[1-Cyclohexyl-4,6-dioxo-2-thioxo-tetrahydro-pyrimidin-(5Z)-ylidenemethyl]-hydrazino}-1,3,7-trimeth yl-3,7-dihydro-purine-2,6-dione | MLS000332932 | SMR000436223 | cid_16682249
TypeSmall organic molecule
Emp. Form.C19H24N8O4S
Mol. Mass.460.51
SMILESCn1c(NNC=C2C(=O)NC(=S)N(C3CCCCC3)C2=O)nc2n(C)c(=O)n(C)c(=O)c12 |w:5.4|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a