Reaction Details Report a problem with these data
Target
P2Y purinoceptor 2
Ligand
BDBM50207816
Substrate
n/a
Ki
0.31±n/a nM
Comments
PDSP_1972
Citation
 Klotz, KN; Vogt, H; Tawfik-Schlieper, H Comparison of A1 adenosine receptors in brain from different species by radioligand binding and photoaffinity labelling. Naunyn Schmiedebergs Arch Pharmacol 343:196-201 (1991) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 2
Synonyms:
ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | P2RY2 | P2RY2_CRIGR | P2Y purinoceptor 2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18813.49
Organism:
HAMSTER
Description:
ADENOSINE A1 ADORA1 HAMSTER::P58825
Residue:
166
Sequence:
VHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLSLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFTLCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPL
  
Inhibitor
Name:
BDBM50207816
Synonyms:
CHEMBL273094 | N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide | N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide (xanthine amine congenere, XAC) | N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide(XAC) | N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide | N-(2-aminoethyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)acetamide | XAC
Type:
Small organic molecule
Emp. Form.:
C21H28N6O4
Mol. Mass.:
428.4848
SMILES:
CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(OCC(=O)NCCN)cc1
Structure:
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