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Target
Transmembrane and immunoglobulin domain-containing 3
Ligand
BDBM50021484
Substrate
n/a
Ki
33.1±n/a nM
Comments
PDSP_2898
Citation
 Olah, ME; Gallo-Rodriguez, C; Jacobson, KA; Stiles, GL 125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor. Mol Pharmacol 45:978-82 (1994) [PubMed] 
Target
Name:
Transmembrane and immunoglobulin domain-containing 3
Synonyms:
ADENOSINE A3 | ADORA3 | Adora3 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25707.75
Organism:
RAT
Description:
Q4V8H0
Residue:
232
Sequence:
MEPLLLLSLALFSDAMVMDEKVKSGVELDTASAICNYDAHYKDHTKYWCRGYFRDSCNIIAFTPNSSNRVALKDTGDQLIITVSCLVKEDTGWYWCGIQRDFARDDMDFTKLIVTDNREDRANGLSPGTSGNRTRSCKTSKAVQKAEGSRMSILIVCVLISGLGIIFLISHMSRGRRSQRNRGVTGKSINRNPQASQAPSMVSIPLTVLPKVPRQNGQQKALQWTGNATKTG
  
Inhibitor
Name:
BDBM50021484
Synonyms:
5-(6-Cyclohexylamino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid ethylamide | Cyclohexyl-NECA | N6-CyclohexylNECA
Type:
Small organic molecule
Emp. Form.:
C18H26N6O4
Mol. Mass.:
390.4368
SMILES:
CCNC(=O)C1OC(C(O)C1O)n1cnc2c(NC3CCCCC3)ncnc12
Structure:
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