Reaction Details Report a problem with these data
Target
Somatostatin receptor type 2
Ligand
BDBM84621
Substrate
n/a
Ki
4.2±n/a nM
Comments
PDSP_378
Citation
 Raynor, K; Murphy, WA; Coy, DH; Taylor, JE; Moreau, JP; Yasuda, K; Bell, GI; Reisine, T Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides. Mol Pharmacol 43:838-44 (1993) [PubMed] 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SSR2_MOUSE | Smstr2 | Somatostatin receptor | Somatostatin receptor 2 | Somatostatin receptor type 2 | Sst2 | Sstr2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41234.26
Organism:
MOUSE
Description:
SOMATOSTATIN SST2 SSTR2 MOUSE::P30875
Residue:
369
Sequence:
MEMSSEQLNGSQVWVSSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWCVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM84621
Synonyms:
BIM 23042
Type:
Small organic molecule
Emp. Form.:
C61H69N11O9S2
Mol. Mass.:
1164.399
SMILES:
CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)C(NC(=O)C(N)Cc2ccc3ccccc3c2)SSC(NC1=O)C(=O)NC(Cc1ccc2ccccc2c1)C(N)=O |r|
Structure:
Search PDB for entries with ligand similarity: