Target
Thromboxane A2 receptor
Ligand
BDBM50002765
Substrate
n/a
Meas. Tech.
ChEMBL_209575 (CHEMBL879433)
Ki
1300±n/a nM
Citation
 Ohshima, ETakami, HSato, HObase, HMiki, IIshii, AKarasawa, AKubo, K Non-prostanoid thromboxane A2 receptor antagonists with a dibenzoxepin ring system. 1. J Med Chem 35:3394-402 (1992) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50002765
Synonyms:
BM 13177 | BM-13177 | CHEMBL8273 | Sulotroban | [4-(2-Benzenesulfonylamino-ethyl)-phenoxy]-acetic acid | [4-(2-Benzenesulfonylamino-ethyl)-phenoxy]-acetic acid (BM 13177) | [4-(2-Benzenesulfonylamino-ethyl)-phenoxy]-acetic acid(sulotroban)
Type:
Small organic molecule
Emp. Form.:
C16H17NO5S
Mol. Mass.:
335.375
SMILES:
OC(=O)COc1ccc(CCNS(=O)(=O)c2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: