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Target
Mu-type opioid receptor
Ligand
BDBM50010532
Substrate
n/a
Meas. Tech.
ChEMBL_146989 (CHEMBL758065)
IC50
0.007000±n/a nM
Citation
 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Synthesis and structure-activity relationships of dynorphin A-(1-8) amide analogues. J Med Chem 33:206-12 (1990) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50010532
Synonyms:
13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid (1-{[1-(1-ethylcarbamoyl-3-methyl-butylcarbamoyl)-4-guanidino-butyl]-methyl-carbamoyl}-4-guanidino-butyl)-amide | CHEMBL441939
Type:
Small organic molecule
Emp. Form.:
C47H73N15O9S2
Mol. Mass.:
1056.308
SMILES:
CCNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1CSSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N1
Structure:
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