Reaction Details Report a problem with these data
Target
Platelet-activating factor receptor
Ligand
BDBM50011078
Substrate
n/a
Meas. Tech.
ChEBML_177423
IC50
2600±n/a nM
Citation
 Bartrolí, J; Carceller, E; Merlos, M; García-Rafanell, J; Forn, J Disubstituted tetrahydrofurans and dioxolanes and PAF antagonists. J Med Chem 34:373-86 (1991) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50011078
Synonyms:
2-{2-[Acetyl-(4-hexadecyloxymethyl-tetrahydro-furan-2-ylmethoxycarbonyl)-amino]-ethyl}-1-ethyl-pyridinium; iodide | CHEMBL264467
Type:
Small organic molecule
Emp. Form.:
C34H59N2O5
Mol. Mass.:
575.8421
SMILES:
CCCCCCCCCCCCCCCCOCC1COC(COC(=O)N(CCc2cccc[n+]2CC)C(C)=O)C1
Structure:
Search PDB for entries with ligand similarity: