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Target
Transcriptional activator protein LasR
Ligand
BDBM50465709
Substrate
n/a
Meas. Tech.
ChEMBL_1788573 (CHEMBL4260307)
IC50
640±n/a nM
Citation
 Soukarieh, F; Williams, P; Stocks, MJ; Cámara, M Pseudomonas aeruginosa Quorum Sensing Systems as Drug Discovery Targets: Current Position and Future Perspectives. J Med Chem 61:10385-10402 (2018) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LasR
Synonyms:
LASR_PSEAE | lasR
Type:
PROTEIN
Mol. Mass.:
26618.24
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_1475312
Residue:
239
Sequence:
MALVDGFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAFEHPVSKPVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVNLGLITL
  
Inhibitor
Name:
BDBM50465709
Synonyms:
8-Azaguanine | CHEBI:63486
Type:
Small organic molecule
Emp. Form.:
C4H4N6O
Mol. Mass.:
152.1142
SMILES:
Nc1nc(O)c2[nH]nnc2n1
Structure:
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