Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetDihydropteridine reductase
LigandBDBM50025878
Substrate/Competitorn/a
Meas. Tech.ChEMBL_50920
Ki 3300±n/a nM
Citation Gessner, WBrossi, AShen, RAbell, CW Synthesis and dihydropteridine reductase inhibitory effects of potential metabolites of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Med Chem28:311-7 (1985) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dihydropteridine reductase
Name:Dihydropteridine reductase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:25554.95
Organism:Rattus norvegicus
Description:ChEMBL_54067
Residue:241
Sequence:
MAASGEARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASASVIVKMTDSFTEQ
ADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTISSHLAT
KHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPSGAAAIAVLPV
TLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGNKRPNSGSLIQVVTTDGKTELTPAY
F
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50025878
NameBDBM50025878
Synonyms:4-(1-Methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-benzene-1,2-diol | CHEMBL323998
TypeSmall organic molecule
Emp. Form.C12H15NO2
Mol. Mass.205.253
SMILESCN1CCC(=CC1)c1ccc(O)c(O)c1 |c:4|
Structure
n/a