Reaction Details Report a problem with these data
Target
4-aminobutyrate aminotransferase, mitochondrial
Ligand
BDBM50488116
Substrate
n/a
Meas. Tech.
ChEMBL_922510 (CHEMBL3076582)
IC50
300±n/a nM
Citation
  TBA Med Chem Res 22:134-146 (2013)    Article 
Target
Name:
4-aminobutyrate aminotransferase, mitochondrial
Synonyms:
Abat | GABT_RAT | Gabat | Gamma-amino-N-butyrate transaminase
Type:
PROTEIN
Mol. Mass.:
56465.74
Organism:
Rattus norvegicus
Description:
ChEMBL_884621
Residue:
500
Sequence:
MAFLLTTRRLVCSSQKNLHLFTPGSRYISQAAAKVDFEFDYDGPLMKTEVPGPRSQELMKQLNTIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYNHPALAKLVQQPQNASTFINRPALGILPPENFVDKLRESLMSVAPKGMCQLITMACGSCSNENAFKTIFMWYRSKERGQRGFSKEELETCMVNQSPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVTDNQQEEARCLEEVEDLIVKYRKKKRTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMSFSKKMMTGGFFHKEEFRPSAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNVAHAGKTLLTGLLDLQAQYPQFVSRVRGRGTFCSFDTPDEAIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSGILADFK
  
Inhibitor
Name:
BDBM50488116
Synonyms:
CHEMBL2283209
Type:
Small organic molecule
Emp. Form.:
C18H19N3O2
Mol. Mass.:
309.3624
SMILES:
NCCCC(=O)N\N=C(\C(=O)c1ccccc1)c1ccccc1
Structure:
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