Target
Cannabinoid receptor 2
Ligand
BDBM50491596
Substrate
n/a
Meas. Tech.
ChEMBL_959211 (CHEMBL2383566)
Ki
2.7±n/a nM
Citation
 Aghazadeh Tabrizi, MBaraldi, PGSaponaro, GMoorman, ARRomagnoli, RPreti, DBaraldi, SRuggiero, ETintori, CTuccinardi, TVincenzi, FBorea, PAVarani, K Discovery of 7-oxopyrazolo[1,5-a]pyrimidine-6-carboxamides as potent and selective CB(2) cannabinoid receptor inverse agonists. J Med Chem 56:4482-96 (2013) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2
Type:
Enzyme
Mol. Mass.:
39366.68
Organism:
Rattus norvegicus (Rat)
Description:
Q9QZN9
Residue:
360
Sequence:
MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILSSQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLDVRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYALRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
  
Inhibitor
Name:
BDBM50491596
Synonyms:
CHEMBL2381786
Type:
Small organic molecule
Emp. Form.:
C28H34N4O2
Mol. Mass.:
458.5952
SMILES:
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(cc12)-c1ccccc1 |TLB:14:15:19:13.18.12,THB:16:15:18.17.19:12|
Structure:
Search PDB for entries with ligand similarity: