Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50038281
Substrate
n/a
Meas. Tech.
ChEMBL_201900 (CHEMBL808191)
Ki
1.68±n/a nM
Citation
 Chumpradit, S; Kung, MP; Vessotskie, J; Foulon, C; Mu, M; Kung, HF Iodinated 2-aminotetralins and 3-amino-1-benzopyrans: ligands for dopamine D2 and D3 receptors. J Med Chem 37:4245-50 (1995) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50038281
Synonyms:
7-((E)-3-Iodo-allylamino)-5,6,7,8-tetrahydro-naphthalen-2-ol | CHEMBL336326
Type:
Small organic molecule
Emp. Form.:
C13H16INO
Mol. Mass.:
329.1767
SMILES:
Oc1ccc2CCC(Cc2c1)NC\C=C\I
Structure:
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