Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50045346
Substrate
n/a
Meas. Tech.
ChEBML_29991
Ki
440.0±n/a nM
Citation
 Jacobson, KA; Shi, D; Gallo-Rodriguez, C; Manning, M; Müller, C; Daly, JW; Neumeyer, JL; Kiriasis, L; Pfleiderer, W Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors. J Med Chem 36:2639-44 (1993) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
45015.65
Organism:
Rattus norvegicus (rat)
Description:
Rat A2A receptors expressed in CHO cells.
Residue:
410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
  
Inhibitor
Name:
BDBM50045346
Synonyms:
1,3-Dimethyl-8-pent-1-enyl-3,7-dihydro-purine-2,6-dione | CHEMBL313646
Type:
Small organic molecule
Emp. Form.:
C12H16N4O2
Mol. Mass.:
248.281
SMILES:
CCCC=Cc1nc2n(C)c(=O)n(C)c(=O)c2[nH]1 |w:3.2|
Structure:
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