Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50051350
Substrate
n/a
Meas. Tech.
ChEMBL_31838 (CHEMBL641515)
Ki
42800±n/a nM
Citation
 Karton, Y; Jiang, JL; Ji, XD; Melman, N; Olah, ME; Stiles, GL; Jacobson, KA Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists. J Med Chem 39:2293-301 (1996) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50051350
Synonyms:
2,3-Dihydro-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one | 2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one | 4'-Hydroxyflavanone | CHEMBL73933
Type:
Small organic molecule
Emp. Form.:
C15H12O3
Mol. Mass.:
240.254
SMILES:
Oc1ccc(cc1)C1CC(=O)c2ccccc2O1
Structure:
Search PDB for entries with ligand similarity: