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Target
D(2) dopamine receptor
Ligand
BDBM50052737
Substrate
n/a
Meas. Tech.
ChEMBL_62079 (CHEMBL672378)
Ki
1715±n/a nM
Citation
 Shah, JH; Kline, RH; Geter-Douglass, B; Izenwasser, S; Witkin, JM; Newman, AH (+/-)-3-[4'-(N,N-dimethylamino)cinnamyl]benzazepine analogs: novel dopamine D1 receptor antagonists. J Med Chem 39:3423-8 (1996) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50052737
Synonyms:
CHEMBL423510 | {4-[(E)-3-(7-Chloro-8-methoxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-propenyl]-phenyl}-dimethyl-amine
Type:
Small organic molecule
Emp. Form.:
C28H31ClN2O
Mol. Mass.:
447.012
SMILES:
COc1cc2C(CN(C\C=C\c3ccc(cc3)N(C)C)CCc2cc1Cl)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: