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Target
Thromboxane A2 receptor
Ligand
BDBM50053757
Substrate
n/a
Meas. Tech.
ChEMBL_209609 (CHEMBL817337)
IC50
1500±n/a nM
Citation
 Heinisch, G; Holzer, W; Kunz, F; Langer, T; Lukavsky, P; Pechlaner, C; Weissenberger, H On the bioisosteric potential of diazines: diazine analogues of the combined thromboxane A2 receptor antagonist and synthetase inhibitor Ridogrel. J Med Chem 39:4058-64 (1996) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50053757
Synonyms:
5-[1-Pyrimidin-5-yl-1-(3-trifluoromethyl-phenyl)-meth-(E)-ylideneaminooxy]-pentanoic acid | CHEMBL129843
Type:
Small organic molecule
Emp. Form.:
C17H16F3N3O3
Mol. Mass.:
367.3224
SMILES:
OC(=O)CCCCO\N=C(/c1cccc(c1)C(F)(F)F)c1cncnc1
Structure:
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