Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50054612
Substrate
n/a
Meas. Tech.
ChEMBL_159327 (CHEMBL769380)
IC50
>10000±n/a nM
Citation
Thaisrivongs, S; Romero, DL; Tommasi, RA; Janakiraman, MN; Strohbach, JW; Turner, SR; Biles, C; Morge, RR; Johnson, PD; Aristoff, PA; Tomich, PK; Lynn, JC; Horng, MM; Chong, KT; Hinshaw, RR; Howe, WJ; Finzel, BC; Watenpaugh, KD Structure-based design of HIV protease inhibitors: 5,6-dihydro-4-hydroxy-2-pyrones as effective, nonpeptidic inhibitors. J Med Chem 39:4630-42 (1996) [PubMed] Article
More Info.:
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF